I mean, there would definitely be no CoE… Otherwise I don’t think it would have impacted his reign so much as his legacy? He would have still built up the Navy etc. He would be Prince of Wales, so Mary would never have a household there, but maybe she would’ve secured a marriage with another country more easily if a match was made with her brother and another royal of that country as well.
I mean, he would’ve definitely married after COA died… ‘who’ is the question; irl François I offered him his daughter Madeleine’s hand in marriage in 1536.